A USPTO examiner’s adverse patentability decision may be reviewed by (appealed to) a higher authority (patent office or federal court). The first appeal is taken to the USPTO Board of Patent Appeals and Interferences. Applicants must file a Notice of Appeal, an appeal brief, and pay the appeal fee within six months of the mailing date of the Examiner’s patent claim rejection [15 USC§1070 and 37 CFR §2.142(a)].